Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
نویسندگان
چکیده
منابع مشابه
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
Rapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant increases in life span, including maximum life span, at each of three test sites. Median survival was extended by an average of 10% in males and 18% in females. Rapamycin attenuated age-associated decline in spontaneous activity in males but not in females. Causes of death were...
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ژورنال
عنوان ژورنال: The Journals of Gerontology: Series A
سال: 2010
ISSN: 1758-535X,1079-5006
DOI: 10.1093/gerona/glq178